ICJEM
Intercontinental Journal of Emergency Medicine

The Intercontinental Journal of Emergency Medicine aims to publish issues related to all fields of emergency medicine and all specialties involved in the management of emergencies in the hospital and prehospital environment of the highest scientific and clinical value at an international level and accepts articles on these topics.

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Letter to the Editor
Comment on: "Early lactate clearance and short-term outcomes in icu patients admitted from the emergency department"
Abstract
This letter comments on the study by Taştemur and Demir evaluating the prognostic significance of early lactate clearance in patients with suspected infection admitted to the intensive care unit from the emergency department. From an emergency medicine perspective, the findings highlight the clinical value of dynamic lactate monitoring during the early resuscitation phase. Early lactate clearance appears to provide meaningful prognostic information beyond static severity scores and may support risk stratification and decision-making during the transition from emergency care to intensive care.

Keywords : Lactate clearance, emergency department, intensive care unit

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Author Contributions

The author is solely responsible for the conception, data collection, analysis, and writing of this manuscript.

Conflict of Interest

The author declare no conflicts of interest.

Financial Disclosure

No financial support was received for the preparation or publication of this letter.


1. Taştemur Ş, Demir E. Prognostic significance of early lactate clearance in patients with suspected infection admitted to the intensive care unit from the emergency department. Intercont J Emerg Med. 2026;4(1):13-17. doi:10.51271/ICJEM-0070
2. Nguyen HB, Rivers EP, Knoblich BP, et al. Early lactate clearance is associated with improved outcome in severe sepsis and septic shock. Crit Care Med. 2004;32(8):1637-1642. doi:10.1097/01.ccm.0000132904.35713.a7
3. Cao Y, Yao S, Shang J, et al. The combination of lactate level, lactate clearance and APACHE II score better predicts short-term outcomes in critically ill patients: a retrospective cohort study. BMC Anesthesiol. 2022;22(1):382. doi:10.1186/s12871-022-01878-0
4. Evans L, Rhodes A, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47(11):1181-1247. doi:10.1007/s00134-021-06506-y
5. Zhang T, Chen L, Kueth G, et al. Lactate’s impact on immune cells in sepsis: unraveling the complex interplay. Front Immunol. 2024;15: 1483400. doi:10.3389/fimmu.2024.1483400
Article available in :
Volume 4, Issue 3, 2026
Page : 69-71
https://doi.org/10.51271/ICJEM-0083
Article Information
Received : 25 Nis 2026
Accepted : 25 May 2026
Published : 19 Eyl 2026
Corresponding Author :

Fatih Alper Ayyıldız: Department of Emergency Medicine, Eskişehir City Hospital, Eskişehir, Turkiye

[email protected]
Citation : Ayyıldız FA. Comment on: early lactate clearance and short-term outcomes in icu patients admitted from the emergency department. Intercont J Emerg Med. 2026;4(3):69-71. doi:10.51271/ICJEM-0083

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