ICJEM

The Intercontinental Journal of Emergency Medicine aims to publish issues related to all fields of emergency medicine and all specialties involved in the management of emergencies in the hospital and prehospital environment of the highest scientific and clinical value at an international level and accepts articles on these topics. This journal is indexed by indices that are considered international scientific journal indices (DRJI, ESJI, OAJI, etc.). According to the current Associate Professorship criteria, it is within the scope of International Article 1-d. Each article published in this journal corresponds to 5 points.

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Original Article
The relationship between patient characteristics, laboratory findings and outcomes of the patients presenting with seizures to the emergency department
Aims: Most patients with epilepsy have recurrent admissions to the emergency department (ED) during the disease. Insufficient information about this patient population causes a mismatch between patients' needs and health care delivery. For this reason, there is a need for objective methods that can be used to monitor seizure patients in EDs and to determine the need for hospitalization. This study aimed to develop management recommendations for patients with active seizures or a history of seizures prior to admission and contribute to the determination of the criteria for the ED follow-up period.
Methods: This study was designed as a single-center, prospective, and observational study and included patients over 18 who presented to the ED for seizures. After the patients were included in the study, demographic and laboratory findings were recorded, and patients were followed up for 30 days for mortality and recurrent seizures.
Results: Seventy-one patients were included in the study. The most known seizure causes were drug incompatibility (15.49%) and infection (9.86%). The most common comorbidities were Hypertension (16.90%), Diabetes Mellitus (12.68%), and cerebrovascular diseases (9.86%). The mortality rate was higher in patients who were hospitalized, had an active infection, and had a high CRP value.
Conclusion: The 30-day mortality is higher in patients presenting to the ED with epileptic seizures; in the advanced age group, patients with active infection have an elevated C-reactive protein in laboratory parameters.


1. Walls RM, Hockberger RS, Gausche-Hill M, editors. Rosen’s emergencymedicine: concepts and clinical practice. Ninth edition. Philadelphia,PA: Elsevier; 2018. 2 p.
2. Girot M, Hubert H, Richard F, et al. Use of emergency departments by known epileptic patients: Anunderestimated problem? Epilepsy Res. 2015;113:1-4.
3. Dixon PA, Kirkham JJ, Marson AG, Pearson MG. National Audit ofSeizure Management in Hospitals (NASH): results of the national auditof adult epilepsy in the UK. BMJ Open. 2015;31;5(3):e007325.
4. Hauser WA, Annegers JF, Rocca WA. Descriptive epidemiology ofepilepsy: contributions of population-based studies from Rochester,Minnesota. Mayo Clin Proc. 1996;71(6):576-586.
5. Fiest KM, Sauro KM, Wiebe S, et al.Prevalence and incidence of epilepsy: a systematic review and meta-analysis of international studies. Neurology. 2017;17;88(3):296-303.
6. Quintana M, Sánchez-López J, Mazuela G, et al. Incidence and mortality in adults with epilepsy innorthern Spain. Acta Neurol Scand. 2021;143(1):27-33.
7. Bozali G, Kose A, Babus SB, Kaleağası SH, Temel GO. Characteristics ofthe patients admitted to the emergency department with seizures andthe factors affecting the frequency of admission. Neurosciences. 2021;26(2):163-170.
8. Forsgren L, Beghi E, Oun A, Sillanpää M. The epidemiology of epilepsyin Europe - a systematic review. Eur J Neurol. 2005;12(4):245-253.
9. Gasparini S, Ferlazzo E, Sueri C, et al.Hypertension, seizures, and epilepsy: a review on pathophysiology andmanagement. Neurol Sci Off J Ital Neurol Soc Ital Soc Clin Neurophysiol.2019;40(9):1775-1783.
10. Shlobin NA, Sander JW. Drivers for the comorbidity of type 2 diabetesmellitus and epilepsy: a scoping review. Epilepsy Behav EB. 2020;106:107043.
11. Cordato DJ, Thomas PR, Ghia D, et al.Decreasing presentations of seizures to emergencydepartments in a large Australian population. 2009;475-478.
12. Avilés RA, Alonso CF, López ML, Martínez FG, Ferrer MEF, BañeresBG. Adults discharged after an epileptic seizure: a model of 30-day riskfor adverse outcomes.
13. Alapirtti T, Waris M, Fallah M, et al. C-reactive protein and seizures in focal epilepsy: avideo-electroencephalographic study. Epilepsia. 2012;53(5):790-796
14. Fujii Y, Yashiro M, Yamada M, et al.Serum procalcitonin levels in acute encephalopathy with biphasic seizures and late reduced diffusion. Dis Markers. 2018;2380179.
15. Zhong R, Chen Q, Li M, Zhang X, Lin W. Elevated blood C-reactive protein levels in patients with epilepsy: a systematic review and meta-analysis. Front Neurol. 2019;18;10:974.
16. Leung WCY, Lau EHY, Kwan, P, Chang RS. Impactof COVID-19 on seizure-related emergency attendances and hospitaladmissions - a territory-wide observational study.Epilepsy & Behavior :E&B, 2021;115:107497. https://doi.org/10.1016/j.yebeh.2020.107497
Volume 2, Issue 2, 2024
Page : 31-35
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