ICJEM
Intercontinental Journal of Emergency Medicine

The Intercontinental Journal of Emergency Medicine aims to publish issues related to all fields of emergency medicine and all specialties involved in the management of emergencies in the hospital and prehospital environment of the highest scientific and clinical value at an international level and accepts articles on these topics.

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Original Article
The usefulness of S100ß protein and fractalkin in predicting traumatic brain injury in pediatric patients with minor head trauma
Abstract
Aims: In this study it was aimed to demonstrate the effectiveness of S100B protein levels which are biomarkers related to central nervous system, and fractalkin levels, which are known to play a role in inflammation processes in prediction trauma induced brain damage. Methods: Patient aged 2 to 18 years who came to the emergency department due to minor head trauma and underwent brain ct were included in our study. It was investigated whether there was a relationship between the two groups, according to the causes of trauma, symptoms at presentation and the level of serum s100b and FCN according to the lesions detected in CCT. Results: The other symptoms including Vomiting, retrograde amnesia, loss of consciousness, confusion, post traumatic amnesia is significantly higher in patients with brain lesions (p<0,05). Patients with lesions on BCT have significantly low Glassgow coma score. (p<0,05). Patients with lesions on BCT have a significantly high S100B and FKN levels. (p<0,05). S100B area under the curve (CUA) 0.700 sensivity is 55%, spesificity is 87.5%. FKN CUA 0,785, sensitivity is 62.5% specifisity is 85%. Conclusions: As a result, the child patients with BCT lesions from minor cranial trauma levels for S100B and FKN levels are significantly higher and can be a criteria for BCT usage in emergency medicine.

Keywords : Child, fractalkinin, head trauma, S100ß

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Article available in :
Volume 1, Issue 4, 2023
Page : 63-66
https://doi.org/10.51271/ICJEM-0017
Article Information
Received : 12 Kas 2023
Accepted : 11 Ara 2023
Published : 30 Ara 2023
Corresponding Author :

Muhammed Semih Gedik: Department of Emergency Medicine, Faculty of Medicine, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkiye

[email protected]
Citation : Gök S, Kilci Aİ, Gedik MS, Hakkoymaz H, Küçük ÖF. The usefulness of S100ß protein and fractalkin in predicting traumatic brain injury in pediatric patients with minor head trauma. Intercont J Emerg Med. 2023;1(4):63-66.

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