ICJEM

The Intercontinental Journal of Emergency Medicine aims to publish issues related to all fields of emergency medicine and all specialties involved in the management of emergencies in the hospital and prehospital environment of the highest scientific and clinical value at an international level and accepts articles on these topics. This journal is indexed by indices that are considered international scientific journal indices (DRJI, ESJI, OAJI, etc.). According to the current Associate Professorship criteria, it is within the scope of International Article 1-d. Each article published in this journal corresponds to 5 points.

EndNote Style
Index
Original Article
Evaluation of children with type 1 diabetes in Kırıkkale
Aims: The aim of this study is to evaluate the clinical laboratory and demographic characteristics of children aged 0-18 with Type 1 Diabetes who applied to Kırıkkale University Hospital.
Methods: Patients who applied to Kırıkkale University Medical Faculty Hospital between January 2011 and January 2021 and were diagnosed with Type 1 diabetes mellitus were included in the study. From file information; age at admission, age at diagnosis and laboratory values at admission were recorded.
Results: Of the children, 48 (48.5%) were boys and 51 (51.5%) were girls. The mean age of all patients was 14.4±2.1 years. It was observed that its frequency increased during the adolescence period. It appeared that patients frequently increased in the autumn and winter months. Vitamin D was low in 74.4% of the patients. Statistical significance was found between HbA1c of those who applied to the hospital with a diagnosis of diabetic ketoacidosis.
Conclusion: It is instructive to investigate the regional characteristics of the disease in terms of genetic and environmental factors that have an important place in the etiology. The findings of our study were consistent with similar studies and literature.


1. Svoren BM, Nicholas J. Diabetes mellitus in children. KliegmanRM, Stanton BF, St Geme JW, Schor NF, Behrman RE (Eds.). NelsonTextbook of Pediatrics. 20th ed. Philadelphia: Elsevier Saunders;2016:2760-2783.
2. Weber DR, Jospe N. Classification of Diabetes Mellitus. KliegmanRM, Stanton BF, St Geme JW, Schor NF, editors. Nelson Textbook ofPediatrics.21th ed. Philadelphia: Elsevier Saunders;2019:11814-11822.
3. Maniatis AK, Goehrig SH, Gao D, Rewers A, Walravens P, KlingensmithGJ. Increased incidence and severity of diabetic ketoacidosis amonguninsured children with newly diagnosed type 1 diabetes mellitus.Pediatr Diabetes. 2005;6(2):79-83.
4. Mayer-Davis EJ, Kahkoska AR, Jefferies C, et al. ISPAD Clinical PracticeConsensus Guidelines: Definition, epidemiology, and classification ofdiabetes in children and adolescents. Pediatric Diabetes, 2018;19(Suppl27):7-19.
5. American Diabetes of Association. Classification and Diagnosisof Diabetes: Standards of medical care in diabetes. Diabetes Care.2019;42(1):13-28.
6. Redondo MJ, Foster NC, Libman IM, et al. Prevalence of cardiovascularrisk factors in youth with type 1 diabetes and elevated body mass index.Acta Diabetol. 2016;53(2):271-277.
7. Singh P, Seth A, Kumar P, Sajjan S. Coexistence of celiac disease & type1 diabetes mellitus in children. Indian J Med Res. 2017;145(1):28-32.
8. Rica I, Mingorance A, Gómez-Gila AL, et al. Achievement of metaboliccontrol among children and adolescents with type 1 diabetes in Spain.Acta Diabetologica, 2017;54(7):677-683.
9. Demir F, Gunoz H, Saka N, et al. Epidemiologic features of type 1diabetic patients between 0 and 18 years of age in İstanbul city. J ClinRes Pediatr Endocrinol. 2015;7(1):49-56.
10. Yesilkaya E, Cinaz P, Andiran N, et al. First report on the nationwideincidence and prevalence of Type 1 diabetes among children in Turkey.Diabet Med. 2017;34(3):405-410.
11. Escobar O, Drash AL, Becker DJ. Managment of the child type1 diabetes. Lifshitz F(ed). Pediatric Endocrinology.5 th.ed NewYork:2007;101-121.
12. Acar S, Paketçi A, Gören Y, et al. Tip 1 diabetes mellitus olgularınıntanı anındaki demografik, klinik ve laboratuvar özelliklerinindeğerlendirilmesi. Türkiye Çocuk Hast Derg. 2018;12(3):173-179.
13. Cotellessa M, Barbieri P, Mazzella M, Bonassi S, Minicucci L, LoriniR. High incidence of childhood type 1 diyabetes in Liguria, Italy, From1989 to 1998. Diabetes Care. 2003;26(6):1786-1789.
14. Green A, Sjolie A.K, Eshoj O. Trends in the epidemiology ofIDDM during 1970-2020 in Fyn County, Denmark. Diabetes Care.1996;19(8):801-806.
15. Aydoğan ZK, Battal F, Doğan D. Tip 1 diabetes mellituslu olgularıntanı ve tedavilerinin retrospektif değerlendirilmesi. Turk J Diab Obes.2021;2:111-117
16. Bayoğlu DS, Akıcı N, Bayoğlu V, Gürbüz T, Nuhoğlu Ç. Tip 1 diyabetliçocukların klinik ve epidemiyolojik özellikleri. Haydarpaşa NumuneEğitim ve Araştırma Hastanesi Tıp Dergisi. 2014;54(2):87-92.
17. Saka N. Günöz H, Öcal G, Yordam N, Kurtoğlu S (Editorler). PediatrikEndokrinoloji; Diyabetes mellitus. Ankara: Kalkan Matbaacılık;2003:415-457.
18. Triolo TM, Armstrong TK, McFann K, et al. Additional autoimmunedisease found in 33% of patients at type 1 diabetes onset. Diabetes Care.2011;34(5):1211-1213.
19. Nilsson J, Akesson K, Hanberger L, Samuelsson U. High HbA1c atonset cannot be used as a predictor for future metabolic control forthe individual child with type 1 diabetes mellitus. Pediatr Diabetes.2017;18(8):848-852.
20. Demir F, Gunoz H, Saka N, et al. Epidemiologic features of type 1diabetic patients between 0 and 18 years of age in Istanbul city. J ClinRes Pediatr Endocrinol. 2015;7(1):49-56.
21. Taşkın E, Yılmaz E, Kılıç M, Ertuğrul S. İnsüline bağımlı diyabetesmellitusun epidemiyolojik özellikleri. FÜ Sağ Bil Derg. 2007;21(2):75-79.
22. Mayer-Davis E, Dabelea D, Crandell J, et al. Nutritional factors andpreservation of C-peptide in youth with recently diagnosed type 1diabetes. Diabetes Care. 2013;36(7):1842-1856.
23. Xin Y, Yang M, Chen XJ, Tong YJ, Zhang LH. Clinical features at theonset of childhood type 1 diabetes mellitus in Shenyang, China. JPaediatr Child Health. 2010;46(4):171-175.
24. Bideci A, Demirel F, Çamurdan O, Cinaz P. Tip 1 diyabetli çocuklardailk başvuru bulgularının değerlendirilmesi. Çocuk Sağlığı Hast Derg.2006;49(2):112-116.
25. Leighton E, Sainsbury CA, Jones GC. A Practical review of C-peptidetesting in diabetes. Diabetes Ther. 2017;8(3):475-487
26. Akyürek N, Atabek ME, Eklioğlu BS. Tip 1 diabetes mellitusluhastaların uzun dönem izlemi: tek merkez deneyimi. Türkiye ÇocukHast Derg. 2015;9(4):243-247
27. Zambrana-Calví GD, Palomo-Atance E, Gourdet ME, León-MartínA, Ballester-Herrera MJ, Giralt-Muiña, P. Lipid changes and theirrelationship with vitamin D levels in children under 18 years with type1 diabetes. Endocrinologia y Nutricion. 2016;63(3):126-131.
28. Pozzilli P, Manfrini S, Crinò A, et al. Low levels of 25- hydroxyvitaminD3 and 1,25-dihydroxyvitamin D3 in patients with newly diagnosedtype 1 diabetes. Horm Metab Res. 2005;37(11): 680-683.
29. Svoren BM, Volkening LK, Wood JR, Laffel LM. Significant vitaminD deficiency in youth with type 1 diabetes mellitus. J Pediatr.2009;154(1):132-134.
30. Louraki M, Katsalouli M, Kanaka-Gantenbein C, et al. The prevalenceof early subclinical somatic neuropathy in children and adolescentswith type 1 diabetes mellitus and its association with the persistenceof autoantibodies to glutamic acid decarboxylase (GAD) and isletantigen-2 (IA-2). Diabetes Res Clin Pract. 2016;117:82-90.
31. Kawasaki E. Type 1 diabetes and autoimmunity. Clin PediatrEndocrinol. 2014;23(4):99-105.
32. Kocabaş A, Kocabaş BA, Karagüzel G, Akçurin S. Tip 1 diabetesmellitus olgularımızın antropometrik ve metabolik izlem özelliklerinindeğerlendirilmesi. Türkiye Çocuk Hastalıkları Dergisi. 2013;7(3):113-118
33. Wolfsdorf J, Glaser N, Sperling M. Diabetic ketoacidosis in infants,children and adolescents. Diabetes Care. 2006;29(5):1150-1159
34. Klingensmith GJ, Tamborlane WV, Wood J, et al. Diabetic ketoacidosisat diabetes onset: Still an all too common threat in youth. J Pediatr.2013;162(2):330-334.
35. Demir K, Büyükinan M, Dizdarer C, et al. Tip 1 diyabetli çocuklardatanıda diyabetik ketoasidoz sıklığı ve ilişkili faktörler. Güncel Pediatri.2010;8(3):52-55
36. Burcul A, Polic K, Bartulovic AM. Characteristics of children withdiabetic ketoacidosis treated in pediatric ıntensive care unit: two-centercross-sectional study in croatia. Medicina. 2019;55(7):362.
37. Bui TP, Werther GA, Cameron FJ. Trends in diabetic ketoacidosis inchildhood and adolescence: a 15-yr experience. Pediatric Diabetes.2002;3(2):82-88.
38. Aminzadeh M, Navidi N, Valavi E, Aletayeb SMH. Childhood onsettype 1 diabetes at a tertiary hospital in south-western Iran during 2000-2015: Rapid increase in admissions and high prevalence of DKA atdiagnosis. Prim Care Diabetes. 2019;13(1):43-48.
39. Neu A, Willasch A, Ehehalt S, Hub R, Ranke MB. Ketoacidosis atonset of type 1 diabetes mellitus in children-frequency and clinicalpresentation. Pediatr Diabetes 2003;4(2):77-81.
40. Sağlam H, Eren E, Çakır ED, Yüce N, Yıldız N, Çakır S. Clinical andlaboratory characteristics of the children with diabetic ketoacidosis/Diyabetik ketoasidozla basvuran cocukların klinik ve laboratuvarozellikleri. J Curr Pediatr. 2008;7(1):94-99.
41. Vicinanza A, Messaaoui A, Tenoutasse S, Dorchy H. Diabeticketoacidosis in children newly diagnosed with type 1 diabetesmellitus: Role of demographic, clinical, and biochemical features alongwith genetic and immunological markers as risk factors. A 20-yearexperience in a tertiary Belgian center. Pediatr Diabetes. 2019; 0(5):584-593.
42. Hanas R, Lindgren F, Lindblad B. A 2-yr national population study ofpediatric ketoacidosis in Sweden: predisposing conditions and insulinpump use. Pediatric Diabetes. 2009;10(1):33-37.
Volume 1, Issue 3, 2023
Page : 37-41
_Footer